IPO Report: Three biotechs are going public this week. Here’s what you should know about them

A flurry of biotech initial public offerings is expected to make landfall next week.

Peloton Therapeutics, Ideaya Biosciences, Inc. and U.K.-based Bicycle Therapeutics Plc are expected to price on Wednesday. The companies are all oncology-focused, and are developing drugs targeting everything from transcription factors to the tumors themselves.

Here’s what you need to know about these three biotechs.

Peloton Therapeutics, Inc.

Despite its name, Peloton Therapeutics has nothing to do with exercise bikes. The biotech’s business hinges instead on two drugs that are designed to block a transcription factor called hypoxia-inducible factor-2 alphaαthat — among other things — regulates how the body responds to low oxygen levels.

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